Sunday, May 26, 2013

California Institute for Regenerative Medicine awarded Sangamo $6.4M to develop its ZFP-genome editing technology for the treatment of beta-thalassemia (加州再生醫學研究所授予Sangamo公司了$ 6.4M開發其 ZFP 基因組編輯技術治療β-地中海貧血)

How the technology work?




Figure 1: Schematic to demonstrate the position and orientation of binding of a ZFNs pair to a specific DNA sequence to enable generation of a double strand break in the DNA.

ZFN Schematic


Figure 2: Schematic to demonstrate potential outcomes of a double-strand break in DNA generated by a pair of ZFNs, gene disruption, gene correction or DNA insertion.


Original Source: http://www.sangamo.com/technology/zf-nucleases.html

Friday, May 24, 2013

Asteroid Mining Mission Revealed by Planetary Resources, Inc. (行星資源公司的小行星採礦任務揭示)


Rule #1 About Reading Blogs or Using Internet In General (閱讀部落格,或是使用互聯網的#1規則)


NASA and Google co-purchased quantum computer, from a Canadian company called D-Wave (based near Vancouver, BC.) (美國宇航局和谷歌共同購買由一家加拿大溫哥華公司製造的量子電腦,D-Wave.)


Original Source: http://www.nasdaq.com/article/google-and-nasa-make-quantum-leap-with-new-computer-cm248327

Low-Energy Nuclear Reaction (LENR) or Cold Fusion Principle (低能量核反應或冷聚變原理)



The hydrogen ions are sucked into the nickel lattice, and then the lattice is oscillated at a very high frequency (between 5 and 30 terahertz). This oscillation excites the nickel’s electrons, which are forced into the hydrogen ions (protons), forming slow-moving neutrons. The nickel immediately absorbs these neutrons, making it unstable. To regain its stability, the nickel strips a neutron of its electron so that it becomes a proton — a reaction that turns the nickel into copper (atomic number from 28 to 29) and creates a lot of energy in the process.

Original source: http://www.extremetech.com/extreme/149090-nasas-cold-fusion-tech-could-put-a-nuclear-reactor-in-every-home-car-and-plane

Human Embryonic Stem Cells Derived by Somatic Cell Nuclear Transfer (通過體細胞核移植製造幹細胞)




http://www.cell.com/abstract/S0092-8674(13)00571-0

http://pubpeer.com/publications/F0CFE0360002C25DC0BEFE28987D70

http://www.nature.com/news/stem-cell-cloner-acknowledges-errors-in-groundbreaking-paper-1.13060

Thursday, May 23, 2013